As seen in
![](https://cdn.shopify.com/s/files/1/0904/2164/files/guardian.png?v=1712139477)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/evening-standard_2d3d38da-69b3-4ee1-8841-87abc99d2120.png?v=1670434537)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/Neom-New_160x.png?v=1682333373)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/indybest_1.png?v=1712137870)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/the-janey-loves.png?v=1696582156)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/97.3.png?v=1686128160)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/Health_Wellbeing.png)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/BBC-Midlands-New.png)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/womans-own-black.png)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/virgin-radio-black.png)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/UK-Health-Radio.png)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/MRS-Logo.png)
![](https://cdn.shopify.com/s/files/1/0904/2164/files/The-Naked-Pharmacy_Badge.png?v=1697450120)
Why Choose Naked?
People
We're driven to help people feel the best they can. People are at the centre of our business. Our pharmacists love to connect for free and find solutions to your health questions.
Speak to a pharmacistPurity
There’s nothing to hide. No synthetics. Just raw ingredients and strong content. We use the full range of bioactives so you get the maximum impact.
Natural Vs SyntheticProven
The science makes us do it, as proven by multiple effectiveness studies. Each supplement uses premium grade rated organic ingredients, clinically tested to pharmaceutical levels.
View ResearchOnline health assessment
Our team of qualified Pharmacists have designed this health assessment to help you understand your health needs better so we can provide you with personalised recommendations.
It only takes 2 minutes and you will instantly receive your personalised health solution.
Our Journal
Arthritis and chronic inflammation: Finding relief with turmeric
What is inflammation?
Inflammation is a biological response of the body's immune system to harmful stimuli such as pathogens or damaged cells. It is a protective mechanism and allows the healing process to begin. Inflammation can be classified as either acute (short-term) or chronic (long-term), it is a critical component of the body's healing process but when it becomes chronic, it can contribute to various diseases and health issues. Therefore, managing inflammation is essential for overall health and well-being.
What causes inflammation?
There are many causes for inflammation, here are a few examples below:
- Infections: Bacteria, viruses, fungi, and parasites
- Physical injury: Cuts, scrapes, or other physical trauma
- Chemical irritants: Exposure to harmful chemicals can cause inflammation.
- Autoimmune reactions: The body’s immune system mistakenly attacks healthy tissues, leading to conditions such as lupus or rheumatoid arthritis.
- Chronic diseases: Conditions like diabetes, obesity, and cardiovascular disease are associated with chronic inflammation.
How is inflammation diagnosed?
Inflammation can be recognised through a blood test. The biomarkers that can help us spot inflammation are C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) which can be elevated. A full blood count is also a useful tool, specifically looking at the white blood cells which are part of our immune system, if these are elevated it can be a sign of an inflammatory response.
The normal CRP level for adults is 0-5 mg/L, an elevated result would be over 5mg/L. The timing of the blood test for CRP can affect results and the best time to take the test is between 8 am and 10 am. CRP levels rise following exercise; it is best to carry out the test before your workout or a few days after. The ESR measures the rate at which the red blood cells separate from the plasma and fall to the bottom of a test tube. The rate is measured in millimetres per hour (mm/hr). The normal range for ESR is 0-22 mm/hr for men and 0-29 mm/hr for women.
The blood test highlights if something is going on, but it doesn’t tell us exactly what it is, therefore, further investigation would be required such as:
- Imaging: X-ray, ultrasounds, Magnetic Resonance Imaging (MRI) or Computed Tomography (CT) scan
- Biopsy: Tissue sample
- Allergy tests: To determine if inflammation is due to an allergic reaction.
- Microbiological tests: Cultures
- Rheumatoid arthritis: Rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibodies.
- Systemic Lupus Erythematosus (SLE): Antinuclear antibodies (ANA) test.
- Inflammatory bowel disease (IBD): Endoscopy and biopsy of the gastrointestinal tract.
What’s the difference between acute and chronic inflammation?
Acute and chronic inflammation are two types of inflammatory responses that the body uses to address different types of harm or injury. They differ in their onset, duration, characteristics, and the underlying mechanisms involved.
Aspect | Acute Inflammation | Chronic Inflammation |
Onset | Rapid (minutes to hours) | Slow (weeks to years) |
Duration | Short-term (days to weeks) | Long-term (months to years) |
Symptoms | Redness, heat, swelling, pain | Less intense, persistent pain, fatigue |
Cells Involved | Neutrophils | Macrophages, lymphocytes |
Purpose | Eliminate cause, start healing | Prolonged response, often harmful |
Outcome | Resolution and healing | Tissue damage, fibrosis |
Acute inflammation is a rapid and typically beneficial response aimed at resolving the initial cause of harm and healing tissue, while chronic inflammation is a prolonged and potentially harmful response that can lead to tissue damage and contribute to chronic diseases.
Gut inflammation
Gut inflammation refers to the inflammatory response within the gastrointestinal (GI) tract. It can affect any part of the digestive system, from the stomach to the rectum. Gut inflammation can result from various causes including infections (bacterial, viral or parasitic), autoimmune disorders (Crohn's disease and ulcerative colitis), food sensitivities (coeliac, lactose) and lifestyle (stress, diet or over-the-counter medications such as long-term use of ibuprofen)
Symptoms of gut inflammation:- Abdominal pain: Cramping or persistent pain in the abdomen.
- Diarrhoea
- Constipation
- Bloating and flatulence
- Blood in stool: Visible blood or black, tarry stools. Always see a doctor if you see blood in your stools.
- Fatigue
- Nausea and vomiting
Treatment of gut inflammation:
There are a few ways we can support our gut and reduce inflammation through our diet such as elimination diets to identify trigger foods. You might have heard of a diet called the AIP diet or the auto-immune protocol. This diet has an elimination phase and a re-introductory phase.
Specific diets such as gluten-free for coeliac disease or low FODMAP which stands for Fermentable oligosaccharides, disaccharides, monosaccharides and polyols for IBS. An anti-inflammatory diet that is rich in fruits, vegetables, whole grains, and healthy fats is a good option too.
Alongside diet, our lifestyle can affect gut inflammation. Focusing on stress management through yoga, meditation and counselling can help. Ensuring you get regular exercise and keep hydrated all make a difference to systemic inflammation.
However, despite making these changes inflammation can persist and there might be a need for medications such as corticosteroids, immune modulators such as Azathioprine and methotrexate, biologic therapies, and probiotics such as Gut Love to restore gut flora balance.
![Gut Love Gut Health Supplement](https://cdn.shopify.com/s/files/1/0904/2164/files/11_b2b49861-b73e-42d0-ad8b-101a5e2879af_2048x2048.jpg?v=1719990748)
Exercise-induced inflammation
Exercise-induced inflammation is a natural and often beneficial response that occurs in the body following physical activity. This type of inflammation can help with muscle repair and adaptation, contributing to increased strength and endurance. However, if not managed properly, it can also lead to overtraining and injury.
Mechanisms of exercise-induced inflammation
- Microtrauma: Exercise, especially high-intensity or resistance training, causes small-scale damage (micro trauma) to muscle fibres. This damage triggers an inflammatory response to repair the tissues.
- Immune response: White blood cells, including neutrophils and macrophages, migrate to the site of muscle damage. These cells release cytokines and growth factors that promote inflammation and initiate the healing process.
- Oxidative stress: Physical activity increases the production of reactive oxygen species (ROS), which can contribute to inflammation. The body’s antioxidant defence usually manages ROS, but excessive production can lead to oxidative stress and inflammation.
Signs of exercise-induced inflammation:
- Muscle soreness or delayed onset muscle soreness (DOMS), typically occurring 24-72 hours after intense exercise.
- Swelling
- Redness and heat: Mild redness and warmth in the muscles due to increased blood flow.
![Barrel of water for ice bath](https://cdn.shopify.com/s/files/1/0904/2164/files/15_2048x2048.jpg?v=1719991614)
Managing exercise-induced inflammation:
- Rest and recovery: Incorporating rest days and active recovery (light activities) is essential.
- Proper nutrition:
- Protein: Essential for muscle repair and growth.
- Antioxidants: Found in fruits and vegetables, help combat oxidative stress.
- Hydration: 2-3 litres of fluid daily. Ensuring electrolytes are also balanced.
- Ice and heat therapy:
- Ice can reduce acute inflammation and pain immediately after exercise.
- Heat can help relax muscles and improve blood flow during recovery.
- Massage and foam rolling: These techniques can help reduce muscle tension and promote blood flow, aiding in the recovery process.
- Supplements
- Curcumin: The active ingredient in turmeric, has anti-inflammatory properties.
- Fish Oil: Rich in omega-3 fatty acids, can reduce inflammation.
![Turmeric](https://cdn.shopify.com/s/files/1/0904/2164/files/8_09d98742-3694-43bb-aa1e-8891b931d7bc_2048x2048.jpg?v=1719990819)
How to avoid excessive inflammation
- Gradual Progression:
- Gradually increasing the intensity and duration of exercise can help prevent excessive inflammation and injury.
- Listening to your body:
- Paying attention to signs of overtraining, such as persistent soreness, fatigue, and decreased performance.
- Adjusting training intensity and volume based on how the body feels.
- Balanced training:
- Incorporating a mix of strength training, cardiovascular exercise, flexibility, and mobility work to balance stress on the body.
Menopause and inflammation
Menopause is a natural biological process that marks the end of a woman's menstrual cycles and reproductive years, typically occurring in the late 40s to early 50s but can be earlier. This transition is accompanied by significant hormonal changes, particularly a decline in oestrogen levels, which can influence various physiological processes, including inflammation.
- Hormonal changes and inflammation
- Decline in oestrogen: Oestrogen has anti-inflammatory properties, and its decline during menopause can lead to increased inflammatory activity. Lower oestrogen levels can affect the immune system, potentially leading to a heightened inflammatory response.
- Increase in pro-inflammatory cytokines: Postmenopausal women often show higher levels of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α). These cytokines play a role in various inflammatory and autoimmune conditions.
- Health implications of increased inflammation
- Cardiovascular disease: Increased inflammation is a risk factor for cardiovascular diseases (CVD) putting menopausal women at higher risk of developing heart disease.
- Osteoporosis: Inflammation can accelerate bone loss, contributing to osteoporosis. Oestrogen helps maintain bone density, and its decline can lead to increased bone resorption and decreased bone formation.
- Metabolic changes: Menopause is associated with changes in body composition, such as increased abdominal fat, which is often visceral fat, this is metabolically active and can produce inflammatory cytokines, further increasing systemic inflammation.
- Joint pain and arthritis: Many women report increased joint pain and stiffness during and after menopause. Oestrogen deficiency can contribute to the development of osteoarthritis and other inflammatory joint conditions.
- Cognitive health: Chronic inflammation is linked to neurodegenerative diseases such as Alzheimer’s. The decline in oestrogen may impact brain health and increase the risk of cognitive decline.
- Treating inflammation during the menopause:
- Hormone Replacement Therapy (HRT): Can help alleviate menopausal symptoms and may reduce inflammation by replenishing oestrogen levels - HRT is not suitable for everyone and should be discussed with a healthcare provider considering the risks and benefits.
- Supplementation:
- Vitamin D and Calcium: Important for bone health.
- Turmeric (Curcumin): Has anti-inflammatory properties.
- Probiotics: Can support gut health, which is linked to systemic inflammation.
![Arthritis in hands](https://cdn.shopify.com/s/files/1/0904/2164/files/Inflammation_-_Blog_Assets_2048x2048.jpg?v=1719990963)
Arthritis
Arthritis is a general term that refers to inflammation of the joints. There are several types of arthritis, each with different causes and manifestations, but inflammation is a common underlying feature.
Types of Arthritis:
- Osteoarthritis (OA): The most common form of arthritis characterised by the breakdown of cartilage in the joints. Traditionally considered a "wear-and-tear" disease that involves low-grade inflammation. Common symptoms include joint pain, and stiffness, which often occur in hips and knees.
- Rheumatoid arthritis (RA): An autoimmune disease where the immune system attacks the synovium (lining of the joints). Chronic inflammation leads to the thickening of the synovium, which can damage cartilage and bone. Common symptoms include symmetrical joint pain, swelling, stiffness (especially in the morning) and fatigue.
- Psoriatic Arthritis (PsA): An inflammatory arthritis associated with psoriasis, a skin condition. Inflammation affects both the skin and joints. Common symptoms include joint pain, stiffness, swelling, and skin plaques characteristic of psoriasis.
- Gout: A type of arthritis caused by the accumulation of urate crystals in the joints. Urate crystals trigger an intense inflammatory response. Common symptoms include sudden, severe attacks of pain, redness, and swelling, typically in the big toe.
Lifestyle Modifications for managing inflammation in arthritis
- Exercise: Regular, low-impact exercise can reduce joint pain and improve flexibility and strength.
- Weight management: Maintaining a healthy weight reduces stress on weight-bearing joints.
- Physical and occupational therapy: Therapists can provide exercises to improve joint function and suggest assistive devices to reduce joint strain.
Alternative therapies:
- Acupuncture: May help reduce pain and improve function in some individuals.
- Herbal supplements: Turmeric (curcumin), ginger, and other supplements have anti-inflammatory properties.
- Surgical interventions: In severe cases, joint replacement or repair surgeries may be necessary to restore function and relieve pain.
![Acupuncture](https://cdn.shopify.com/s/files/1/0904/2164/files/12_2bd8751b-5b93-42db-a7d7-ef586f898e2b_2048x2048.jpg?v=1719991710)
How to reduce inflammation
Reducing inflammation in the body involves a multi-faceted approach that includes dietary changes, lifestyle modifications, and sometimes medical interventions.
Lifestyle modifications
- Regular exercise:
- Moderate exercise: Activities like walking, swimming, and cycling can reduce inflammation. Aim for at least 30 minutes of moderate exercise most days of the week.
- Strength training: Helps build muscle and improve metabolic health.
- Maintain a healthy weight: Excess body fat, especially around the abdomen, is linked to increased inflammation. Achieving and maintaining a healthy weight through diet and exercise can significantly reduce inflammation.
- Stress Management:
- Mindfulness and meditation - Reduce stress through meditation, self-care, journalling, and mindset
- Adequate sleep: Aim for 7-9 hours of quality sleep per night. Poor sleep can increase inflammation.
- Hydration: Drink plenty of water throughout the day to help flush out toxins and support overall health.
- Environmental: Minimise exposure to environmental pollutants and chemicals. Household Products – try to use natural and non-toxic cleaning and personal care products.
- Smoking: Quit smoking to reduce inflammation and improve overall health.
![Hydration](https://cdn.shopify.com/s/files/1/0904/2164/files/13_e6484ea5-112f-46a2-99d7-84f453a0a456_2048x2048.jpg?v=1719991039)
Inflammatory and anti-inflammatory foods:
Here are some of the top pro-inflammatory foods. Consuming these foods excessively may contribute to inflammation in the body. Conversely, incorporating anti-inflammatory foods can help reduce inflammation.
Pro-inflammatory |
Anti-inflammatory |
Processed Food |
Fruit - Berries |
Sugar-Sweetened Beverages |
Vegetables – Leafy Greens |
Refined Carbohydrates |
Whole Grains |
Fried Foods |
Healthy fats |
Alcohol |
Spices and Herbs |
Artificial trans-fat - Margarine |
Dark Chocolate |
Artificial sweeteners |
Green tea |
Processed Meats |
Extra virgin olive oil |
![Natruflex Turmeric Supplement](https://cdn.shopify.com/s/files/1/0904/2164/files/9_072a31c1-c9da-4573-ad79-45227dba46fe_2048x2048.jpg?v=1719991076)
Best supplements for pain and inflammation – Natruflex Turmeric
Turmeric is often praised for its anti-inflammatory properties due to its active compound called curcumin a bioactive compound which is a potent anti-inflammatory agent. Curcumin has been shown to inhibit inflammatory molecules in the body, such as cytokines (TNF-alpha, interleukins), enzymes (COX-2), and transcription factors (NF-kB), which play a key role in the inflammatory process. Curcumin modulates several signalling pathways involved in inflammation, which helps reduce inflammation at the molecular level.
Curcumin acts as a powerful antioxidant, neutralizing free radicals that contribute to oxidative stress and inflammation. Scavenging free radicals and enhancing the activity of antioxidant enzymes in the body, curcumin helps protect cells from oxidative damage.
Curcumin has potential benefits for cardiovascular health by improving endothelial function, lowering cholesterol levels, and reducing inflammation in blood vessels.
Some research indicates that curcumin may support brain health by promoting neuroplasticity and reducing inflammation associated with neurodegenerative diseases.
Curcumin’s bioavailability is typically low when taken alone. However, combining it with piperine (found in black pepper) enhances absorption and can improve its effectiveness. Our Natruflex Turmeric contains piperine and magnesium to help aid absorption and improve muscle and nerve function.
![Coffee](https://cdn.shopify.com/s/files/1/0904/2164/files/10_52fb983d-2116-4c49-83d1-ec3ff62b15ea_2048x2048.jpg?v=1719991118)
A common question – Is coffee inflammatory?
The relationship between coffee consumption and inflammation is complex and can vary based on individual factors.
Potential anti-inflammatory effects of coffee:
- Coffee is rich in antioxidants.
- Polyphenols
- Liver Health: Some studies suggest that coffee consumption may protect against liver inflammation and reduce the risk of liver diseases like non-alcoholic fatty liver disease (NAFLD).
Caveats:
The effects of coffee on inflammation can vary among individuals. Some people may experience increased inflammation or sensitivity to caffeine. Caffeine is a stimulant found in coffee and can affect individuals differently. In some people, excessive caffeine intake may contribute to inflammation or exacerbate existing inflammatory conditions. Sweeteners and creamers added to coffee can contain sugars, artificial additives, or trans fats, which may promote inflammation if consumed in excess.
Coffee is acidic, and some people with gastrointestinal conditions may experience irritation or inflammation in the digestive tract.
Current research and findings:
- A systematic review and meta-analysis published in the British Journal of Nutrition (2014) found that moderate coffee consumption was associated with lower levels of markers of inflammation, such as C-reactive protein (CRP).
- Another study published in the American Journal of Clinical Nutrition (2016) suggested that coffee consumption was inversely associated with markers of inflammation, but the effects varied by genetic factors and individual response.
- On the balance of risk, it is probably best to consume coffee in moderation (typically 1-3 cups per day) is generally considered safe. However, pay attention to how your body responds to coffee. If you notice increased inflammation, digestive issues, or other adverse effects, consider reducing your intake. Another thing to consider is organic coffee to minimise exposure to pesticides and other contaminants.
Speak to our expert pharmacists today
A key element of our vision is accessibility to our expert advice service; allowing customers to make a personalised and considered decision when it comes to their health.
Our pharmacists are on hand Monday – Friday 9 am – 5 pm. Book your free consultation today! Book Now!
Charlotte Parker-Lennox
![Charlotte Parker-Lennox](https://cdn.shopify.com/s/files/1/0904/2164/files/image_50432769_240x240.jpg?v=1718180071)
Charlotte is a pharmacist with 6 years of experience working in retail pharmacy and integrated urgent care (IUC) alongside nurses, paramedics and doctors. She has changed the direction of her career to support people with a holistic approach to wellness by treating the root cause of your health concerns. She enjoys an outdoor challenge, completing marathons and cycling adventures around the UK.
From fatigue to weight changes: Signs your thyroid might be overactive or underactive
The thyroid
The thyroid is a small, butterfly-shaped gland located in the front of the neck. It has two lobes (right and left) connected by a narrow piece of tissue called the isthmus and it is located in front of the trachea (windpipe). The thyroid produces a thyroid hormone called thyroxine (T4 – 4 iodine atoms) which is converted to triiodothyronine (T3 – 3 iodine atoms). T3 is biologically active and regulates many bodily functions.
If our body detects that these thyroid hormones are too low, the pituitary gland in our brain releases another hormone called thyroid-stimulating hormone (TSH). These hormones play a crucial role in regulating the body's metabolism, energy production, and overall hormonal balance.
How to test thyroid function
A thyroid blood test is used to check thyroid function. The thyroid function test looks at the three thyroid hormones, TSH, T4 and T3 to determine whether your thyroid is working well (euthyroid), underactive (hypothyroidism) or overactive (hyperthyroidism). It is always a good idea to test for all these hormones rather than just TSH to get a better picture about what is going on in the body. Alongside thyroid hormones are thyroid antibodies these are tested to determine whether an autoimmune disease like Hashimoto’s or Graves’ disease is present.
Thyroid hormones – Normal levels and units
![](https://cdn.shopify.com/s/files/1/0904/2164/files/Blood_Pressure_Chart2_3_1024x1024.png?v=1718706684)
Source – British Thyroid Foundation
Hypothyroidism (Underactive Thyroid) is mostly seen in women between the ages of 40-50 and is seen in women ten times more often than men, and it often occurs during the menopausal years. Hyperthyroidism (overactive thyroid) is less prevalent in the population.
What causes thyroid problems
There are many reasons why the thyroid might experience dysregulation. Below are some examples:
- Autoimmune disorders: Such as Hashimoto's Thyroiditis or Graves' Disease
- Iodine deficiency: Iodine is essential for thyroid hormone production. A deficiency can result in hypothyroidism and goitre (enlarged thyroid gland).
- Thyroid surgery: Removal of part or all of the thyroid gland can lead to hypothyroidism due to a decreased ability to produce thyroid hormones.
- Radiation therapy: Radiation treatment for cancers of the head and neck can damage the thyroid gland, potentially leading to hypothyroidism.
- Medications: Certain medications, such as lithium (mood stabiliser) and amiodarone (anti-arrhythmic) can interfere with thyroid function and cause hypothyroidism or hyperthyroidism.
- Genetic factors: A family history of thyroid disorders can increase the risk of developing similar conditions.
- Thyroid nodules: Benign or malignant lumps in the thyroid gland can affect its function, sometimes causing hyperthyroidism or requiring surgical intervention that leads to hypothyroidism.
- Pregnancy and postpartum changes: Pregnancy can sometimes trigger thyroid problems, particularly postpartum thyroiditis, which can cause temporary hyperthyroidism followed by hypothyroidism.
- Pituitary disorders: The pituitary gland regulates thyroid function through thyroid stimulating hormone (TSH). Disorders of the pituitary can affect thyroid hormone levels.
- Infections and inflammation: Infections or inflammatory conditions affecting the thyroid (thyroiditis) can disrupt its normal function causing either hypo- or hyperthyroidism.
- Diet and lifestyle factors: Poor diet, stress, and lack of sleep can indirectly affect thyroid health by influencing overall hormonal balance and immune function.
![Tired women](https://cdn.shopify.com/s/files/1/0904/2164/files/Thyroid_-_Blog_banner_2_2048x2048.jpg?v=1718809583)
Underactive thyroid
An underactive thyroid is when the thyroid isn’t producing sufficient thyroid hormones, this is called hypothyroidism. If you have hypothyroidism or are wondering if you do, you will likely have experienced a few of the following symptoms:
Early signs of hypothyroidism (Underactive thyroid)
- Fatigue
- Persistent tiredness and a general lack of energy
- Weight gain
- Feeling unusually cold or having an intolerance to cold temperatures.
- Dry skin and hair
- Constipation
- Muscle weakness and aches
- Depression
- Memory issues
- Slowed heart rate
- Puffiness, especially around the eyes
If you are experiencing these symptoms, it is recommended to go to your GP for a blood test to check your thyroid hormone levels.
If you do have hypothyroidism then you will have an elevated TSH level with low T4 levels. Around 2 in 100 people have hypothyroidism in the UK (Source – Hypothyroidism – Thyroid UK).
However, you might find your TSH levels are elevated but your T4 is normal, this is called subclinical hypothyroidism which affects around 8-10% of the population (Source – Hypothyroidism – Thyroid UK). In other words, it's a mild form of hypothyroidism where the thyroid hormone levels are still within the normal range, but TSH levels are elevated.
Causes
- Autoimmune conditions like Hashimoto's and lack of Iodine.
- Pregnancy due to hormonal changes
Treatment
To treat hypothyroidism, a form of hormone replacement therapy called Levothyroxine is a synthetic thyroxine (T4) is used. This medication normalises hormone levels and alleviates symptoms.
![Pink Scale](https://cdn.shopify.com/s/files/1/0904/2164/files/12_2048x2048.jpg?v=1718809680)
Why is it difficult to lose weight with hypothyroidism?
Losing weight with hypothyroidism is often more challenging than without. Here are a few reasons why it can be harder:
- Slowed metabolism: Thyroid hormones (T3 and T4) play a crucial role in regulating metabolism
- Fatigue and low energy levels: Reduced motivation and capacity to exercise regularly can lead to fewer calories being burned
- Water retention: Retaining water leads to bloating and weight gain that is not related to fat
- Appetite and food cravings: Hormonal imbalances can affect appetite and lead to increased cravings for high-calorie foods, particularly carbohydrates and sugars.
- Insulin resistance: Decreased insulin sensitivity can lead to higher blood sugar levels and increased fat storage, particularly around the abdomen.
- Mood and mental health: Exacerbating depression and anxiety, which can impact eating habits, physical activity, and overall motivation.
- Slower digestive function: Constipation and gastrointestinal discomfort
Overactive thyroid
The opposite of hypothyroidism is hyperthyroidism. This is when the thyroid gland produces excessive amounts of thyroid hormones. Blood tests can show a suppressed TSH level and elevated T4 and T3 hormones.
Early warning signs of overactive thyroid:
- Weight loss
- Feeling unusually warm or sweating excessively
- Rapid or irregular heartbeat
- Nervousness and anxiety
- Tremors
- Increased bowel movements or diarrhoea
- Fatigue and muscle weakness
- Difficulty sleeping
- Thinning hair or hair loss
Causes
- Autoimmune disorders such as Graves' Disease
- Inflammation of the Thyroid or postpartum thyroiditis.
- Excessive Iodine Intake: Consuming too much iodine, either through diet or contrast dyes used in medical imaging tests can lead to hyperthyroidism.
Treatment
Medication
Carbimazole and Propylthiouracil - These medications inhibit the production of thyroid hormones by interfering with the thyroid gland's ability to use iodine.
Beta blockers such as Propranolol, Atenolol and Metoprolol -These medications help alleviate symptoms such as rapid heart rate, palpitations, tremors, and anxiety by reducing the heart rate.
Radioactive iodine therapy
Radioactive iodine is taken orally and selectively absorbed by the overactive thyroid cells and destroys them. This treatment is done once and gradually reduces thyroid hormone production over weeks to months. The downside is that this often results in permanent hypothyroidism, requiring lifelong thyroid hormone replacement therapy.
Surgery
Partial or Total Thyroidectomy is the surgical removal of part of or all the thyroid gland.
This might be recommended for individuals who cannot tolerate medications, are not suitable for radioactive iodine therapy or have large goitres (enlarged thyroid gland). After a total thyroidectomy, thyroid hormone replacement therapy is necessary as the body can no longer make its own thyroid hormones.
The thyroid during menopause and pregnancy
Pregnancy:
Women with hypothyroidism who are pregnant or planning to become pregnant need careful monitoring and may require higher doses of levothyroxine to support proper thyroid hormone levels. There is also a risk of postpartum thyroiditis that can happen to any pregnant woman. It starts off with hyperthyroidism for 1-4 months and then to hypothyroidism in months 4-8 postpartum. At around 12-18 months the thyroid hormones level out and euthyroid is established in most cases. Pregnancy can lead to hypothyroidism through conditions like postpartum thyroiditis or exacerbation of pre-existing autoimmune thyroid conditions. Diagnosing and managing hypothyroidism effectively during pregnancy is essential to ensure the health and well-being of both the mother and the developing foetus.
![Women menopause](https://cdn.shopify.com/s/files/1/0904/2164/files/6_6ab0544a-df07-48f2-8cd4-14beb88ec94d_2048x2048.jpg?v=1718809681)
Menopause
Menopause can influence thyroid hormone levels, leading to changes in thyroid function resulting in subclinical hypothyroidism or hypothyroidism. Some symptoms of menopause such as fatigue, weight gain, mood changes and memory problems can overlap with symptoms of hypothyroidism. It is essential for women experiencing these symptoms during menopause to undergo thyroid function testing to distinguish between menopausal symptoms and thyroid-related issues.
Menopause may also be associated with an increased risk of developing thyroid nodules or goitre (enlarged thyroid gland). Hormonal changes during menopause, particularly fluctuations in oestrogen levels, may contribute to thyroid growth or nodules.
Women with autoimmune thyroid disorders like Hashimoto's thyroiditis or Graves' disease may experience fluctuations in disease activity during menopause.
![Seaweed](https://cdn.shopify.com/s/files/1/0904/2164/files/1_88ffdcdb-db33-4446-b956-7452dafcd474_2048x2048.jpg?v=1718809681)
Diet
There are things we can do to protect our thyroid gland through the food we consume. The micronutrient Iodine is required to make the T4 and T3 hormones, therefore its intake is essential for thyroid function. Consuming foods high in iodine such as seaweed, dairy products and seafood and foods rich in selenium (Brazil nuts, sunflower seeds) and zinc (meat, shellfish) support thyroid function.
If you already have thyroid problems avoid consuming soy products and cruciferous vegetables (broccoli, cabbage, cauliflower) in excess as they are goitrogenic and can interfere with thyroid function. You don’t have to avoid these foods but eat them in moderation; cooking these vegetables can reduce their goitrogenic effect.
Regular physical activity to help manage weight, improve mood, and boost overall energy levels. Engage in regular physical activity, including both aerobic exercises (like walking, running, cycling) and strength training exercises.
Aim for at least 150 minutes of moderate aerobic activity or 75 minutes of vigorous activity each week, along with muscle-strengthening activities on two or more days a week.
Incorporate more physical activity into your daily routine, such as taking the stairs instead of the elevator, walking during breaks, or doing household chores.
![Woman yoga mats](https://cdn.shopify.com/s/files/1/0904/2164/files/10_2048x2048.jpg?v=1718809681)
Lifestyle Modifications
Sleep: Ensure you get adequate sleep, as poor sleep can disrupt hormones that regulate appetite and metabolism. Aim for 7-9 hours of quality sleep per night.
Stress Management: Practice stress-reducing techniques such as meditation, yoga, deep breathing exercises, or engaging in hobbies. Chronic stress can affect weight and overall health.
Support System: Seek support from friends, family, or a weight loss group. Having a support system can provide motivation and accountability.
![Saffrosun Energy Saffron Supplement](https://cdn.shopify.com/s/files/1/0904/2164/files/7_f29ae358-bc60-4387-9aa0-5e4aab5a8c15_2048x2048.jpg?v=1718809681)
Thyroid Supplements
Alongside diet and lifestyle changes we might just need a little bit more support to keep our thyroid healthy.
Our Saffrosun Energy contains Saffron, Vitamin D and Iodine. Saffron may support thyroid function through its anti-inflammatory, antioxidant, and immune management qualities, as well as by improving mood and metabolic health.
Vitamin D supports the thyroid gland by regulating hormone production, regulating the immune system, reducing inflammation, supporting calcium balance and potentially reducing the risk of autoimmune thyroid diseases. And finally, Iodine is key for thyroid function, supporting the synthesis and regulation of thyroid hormones, preventing goitre and ensuring proper growth and metabolic regulation.
We don’t recommend this supplement for anyone with hyperthyroidism. However, those with hypothyroidism, those taking thyroid replacement therapy or those with normal thyroid function can.
Saffrosun Calm is an alternative for those with hyperthyroidism. It contains Saffron, Vitamin D and Vitamin B12. The benefits of Saffron and Vitamin D on the thyroid can still be experienced.
Speak to our expert pharmacists today
A key element of our vision is accessibility to our expert advice service; allowing customers to make a personalised and considered decision when it comes to their health.
Our pharmacists are on hand Monday – Friday 9 am – 5 pm. Book your free consultation today! Book Now!
Charlotte Parker-Lennox
![Charlotte Parker-Lennox](https://cdn.shopify.com/s/files/1/0904/2164/files/image_50432769_240x240.jpg?v=1718180071)
Unveiling the power of Black Garlic: A natural solution for blood pressure
What is blood pressure?
Blood pressure is made up of 2 numbers. The top number is called the systolic blood pressure and measures the pressure your heart is under when blood is pumped out around the body. The bottom number is called the diastolic blood pressure and measures the pressure in our vessels between heartbeats. Blood pressure is measured in millimetres of mercury (mmHg). You may also have heard of high blood pressure referred to as hypertension. In general, women have lower blood pressure than men, this difference decreases as women enter the menopause.
Blood pressure differs depending on your age and this can be seen below:
Blood pressure ranges for adults – 16yrs+
Low BP is classed as under 90/60 mmHg
Ideal BP – Between 90/60 mmHg and 120/80 mmHg
Pre-high blood pressure – Between 120/80 mmHg and 140/90 mmHg
High BP - Over 140/90 mmHg. For over 80-year-olds, this would be 150/90 mmHg
![Blood Pressure Chart](https://cdn.shopify.com/s/files/1/0904/2164/files/Blood_Pressure_Chart2_480x480.jpg?v=1718111268)
Source: Blood Pressure UK
How can I check my blood pressure?
There are many ways you can check your blood pressure. You can go to your local pharmacy for a free blood pressure check, call your GP surgery or take it yourself at home with a blood pressure monitor. Blood pressure monitors can be bought from pharmacies, big retailers and online.
If you do decide to take your own blood pressure at home here are a few tips to try and prevent an inaccurate reading:
- Drinking caffeine or smoking should be stopped 30 minutes prior
- Give yourself 5 minutes of quiet time before attempting to take the reading
- Take your blood pressure seated with your legs uncrossed and flat on the floor
- Place the blood pressure cuff around your bare arm and make sure the wire is facing upwards and in a central position.
- Place your arm in a relaxed bent position, preferably resting on a table or the arm of a chair
- Don’t talk whilst your blood pressure is being taken
- Press the start button
- Document the reading. Such as 120/80
- Do this 3 times with a 1–2-minute pause in between
If you are trying to track and compare your blood pressure it is recommended to take your blood pressure at the same time each day.
When getting your blood pressure done at the pharmacy or GP surgery most of the above will be done for you but you may find that the reading is higher than when you take it yourself at home. This could be due to something called “white coat syndrome” which is when just being in a healthcare setting increases blood pressure due to anxiety, stress or worry. GPs may offer you a portable 24-hour blood pressure monitor to take home. The monitor measures your blood pressure at regular intervals throughout the day whilst doing your day-to-day activities.
Try taking your blood pressure in both arms and seeing if there is a difference. A small difference in blood pressure readings (around 10 mmHg) between each arm is normal. However, a difference of more than 10 mmHg might be a sign to talk to your doctor. The difference can be in the top number or the bottom number. This could be a sign of peripheral artery disease or developing heart disease in future.
![Blood pressure monitor](https://cdn.shopify.com/s/files/1/0904/2164/files/Blood_Pressure_-_Blog_banner_1_2048x2048.jpg?v=1718101074)
When is the best time to take blood pressure?
The best time to take your blood pressure is twice a day, in the morning and in the evening to get an overall view of how your blood pressure is doing throughout the day.
In the morning, our blood pressure is at its lowest and in the evening between 4 pm and 6 pm, it is at its highest. Our blood pressure can fluctuate by up to 30% throughout the day due to our hormones, our activity level and eating habits.
Ultimately, the best time to take your blood pressure is when it suits you and your lifestyle.
What causes high blood pressure?
There are many causes for high blood pressure. These can be singular or additive or because of a health condition:
- Sedentary lifestyle
- Poor diet
- High stress levels
- Age – Over 50 years old
- Smoking
- Overconsumption of alcohol
- Overweight
- Lack of physical activity
- High salt intake
- Family history of high blood pressure especially in black and Asian populations
High blood pressure can also be caused by other health conditions such as:
- Diabetes
- Kidney problems
- Sleep apnoea
- Thyroid problems
![Matches and Cigarette broken](https://cdn.shopify.com/s/files/1/0904/2164/files/Blood_Pressure_-_Blog_banner_2_2048x2048.jpg?v=1718101169)
Signs of high blood pressure
High blood pressure doesn’t often result in symptoms until blood pressure is at extremely high levels. You may not realise we have high blood pressure and feel completely normal which is why we should be checking it more frequently as we age. However, there are some physical signs and symptoms that could occur to look out for:
- Visual disturbance – blurred vision, floaters
- Headaches
- Shortness of breath
- Nosebleeds
Blood pressure during the menopause and pregnancy
Hormonal changes such as menopause can indirectly result in higher blood pressure because oestrogen drops during menopause. This female hormone plays a vital role in protecting our cardiovascular system. It stimulates our blood vessels to relax and widen allowing blood to flow more easily. Oestrogen dropping during the menopause has been linked to an increased risk of cardiovascular disease therefore keeping an eye on our blood pressure is recommended.
Blood pressure during pregnancy normally decreases in the first and second trimesters, however high blood pressure can occur and result in the following:
Chronic hypertension
This is high blood pressure before 20 weeks gestation — a woman with high blood pressure before week 20 of pregnancy is likely to have pre-existing high blood pressure.
Gestational hypertension
This is high blood pressure that is new and occurs after 20 weeks' gestation and there is no protein found in the urine.
Pre-eclampsia
This is new high blood pressure presenting after 20 weeks gestation with significant protein from in urine. Pre-eclampsia is a multi-system disorder which can affect the organs of the mother. It is a concern and seeking medical advice immediately is needed. Some of the physical symptoms of pre-eclampsia include vision disturbances, severe headaches, sudden swelling of the face, hands/feet, vomiting and breathlessness.
What causes low blood pressure?
Movements such as going from lying to standing up can sometimes make us feel lightheaded or dizzy for a brief period of time. This is due to something called postural hypotension. This can occur when you are dehydrated due to lower blood volume.
Medications that are taken to lower blood pressure may be taken incorrectly or too much taken can result in low blood pressure. This can also happen with water tablets (diuretics) and heart disease.
Low blood pressure can sometimes also be a sign of a life-threatening emergency such as sepsis, an allergic reaction (anaphylaxis) or heavy blood loss.
What are low blood pressure symptoms?
Low Blood pressure is below 90/60 mmHg and may be accompanied by some of the symptoms below:
- Dizziness
- Lightheaded
- Fainting
- Tiredness
- Confusion
- Falling
How to reduce high blood pressure?
Blood pressure tablets to treat high blood pressure may be prescribed to you. These blood pressure medications are split into various categories and have different mechanisms of action. Below are some of the main groups of medication for high blood pressure.
- Angiotensin converting Enzyme (ACE) inhibitors such as ramipril. Common side effects include a dry cough, dizziness and headaches
- Calcium Channel blockers such as amlodipine. Common side effects include ankle swelling, constipation and headaches
- Angiotensin receptor blockers (ARB) such as candesartan. Common side effects include headaches, dizziness
- Diuretics such as Bendroflumethiazide. Common side effects include needing to go to the bathroom more frequently, postural hypotension and increased thirst.
The timing of your blood pressure medication is down to personal preference if taking a once-a-day dosage. It might be a clever idea to take blood pressure medication at night to minimise the risk of falls and dizziness. However, this wouldn’t be a good idea if taking diuretics due to the side effects of urinary frequency; these would be best taken in the morning.
Statins are also another group of medications that can indirectly lower your blood pressure by reducing cholesterol especially low-density lipoproteins (LDL). Too much of this type of cholesterol can build up along the artery walls and create a narrowing of the arteries resulting in an increase in blood pressure
![Black Garlic](https://cdn.shopify.com/s/files/1/0904/2164/files/Blood_Pressure_-_Blog_banner_3_2048x2048.jpg?v=1718101308)
How to lower blood pressure naturally
We offer a few natural alternatives that could help reduce blood pressure and can be used alongside blood pressure medications and other prescribed medication such as statins:
- Black Garlic
- Marine Magnesium
- Metabolic Gold
These three supplements can be taken together and work in different ways.
Black Garlic with Vitamin D
Our Black Garlic contains fermented black garlic which is more potent than normal raw garlic. Normal garlic contains Allicin and during the fermentation process, Allicin converts to S-Allyl Cysteine (SAC) which is the natural compound responsible for stimulating circulation and lowering blood pressure. Black Garlic can help blood flow more easily and this is why we wouldn’t recommend taking it if you are on any blood thinners or antiplatelets such as Warfarin, Apixaban, Clopidogrel and Aspirin.
Metabolic Gold
Our Metabolic Gold contains Bergamot fruit extract and Artichoke Leaf extract. Both ingredients may improve certain risk factors for heart disease. Lowering cholesterol levels to avoid atherosclerosis and build up along the vessel walls which narrows them resulting in increased blood pressure.
Marine Magnesium
Our Marine Magnesium can also help with blood pressure by relaxing the blood vessels.
Nutrition
Other than supplements we can help our blood pressure through the food we eat and don’t eat.
- Reduce salt intake to less than 6g per day – Not all salts are the same. Here we are referring to table salt that contains sodium.
- Increase consumption of healthy unsaturated fats - oily fish, avocado, eggs and nuts/seeds.
- Reduce consumption of artificial sugars and saturated fats.
- Reduce alcohol intake – 14 units weekly. Try to spread them over a few days rather than consuming them all at once as our liver finds it hard to process. What does a unit of alcohol look like? 40% spirit (25ml), wine (100ml), Beer (180ml).
![Cycling Sunset](https://cdn.shopify.com/s/files/1/0904/2164/files/Blood_Pressure_-_Blog_banner_4_2048x2048.jpg?v=1718101370)
Exercise
The main thing when it comes to exercise is to do something you enjoy and that you can be consistent with. For heart health, we need to do some form of cardiovascular exercise such as walking, running, swimming or cycling.
150 minutes of moderate intensity (you can still hold a conversation) cardio or 75 minutes of vigorous intensity (you can only speak a few words) cardio a week is recommended by the NHS. It has now been shown that muscle mass and cardio-respiratory fitness are linked with longevity. A full body strength training session is an effective way to do this, aiming for twice a week to maintain muscle mass especially as we age.
Speak to our expert pharmacists today
A key element of our vision is accessibility to our expert advice service; allowing customers to make a personalised and considered decision when it comes to their health.
Our pharmacists are on hand Monday – Friday 9 am – 5 pm. Book your free consultation today! Book Now!
Charlotte Parker-Lennox
![Charlotte Parker-Lennox](https://cdn.shopify.com/s/files/1/0904/2164/files/image_50432769_240x240.jpg?v=1718180071)
Charlotte is a pharmacist with 6 years of experience working in retail pharmacy and integrated urgent care (IUC) alongside nurses, paramedics and doctors.
She has changed the direction of her career to support people with a holistic approach to wellness by treating the root cause of your health concerns. She enjoys an outdoor challenge, completing marathons and cycling adventures around the UK.
Sign up to our newsletter and get 20% off!
No junk, (just like our supplements)! Just naturally intelligent science, podcasts and product news.
*Discount code valid on The Naked Pharmacy product range only and for first onetime purchase order only. Cannot be used in conjunction with any other offers. We will never share your details with any 3rd parties, please review our Privacy Policy for more information.